Neurobiology and Medication Adherence Concepts NURS 6630
Neurobiology and Medication Adherence Concepts NURS 6630
A Sample Answer For the Assignment: Neurobiology and Medication Adherence Concepts NURS 6630
Neurons are information messengers whose role is to transmit information between the areas of the brain and the rest of the nervous system. They have three main parts namely the cell body, axon, and the dendrites (Kringelbach et al., 2020). The cell body is made up of a nucleus and cytoplasm and produces protein required to construct other parts of the neuron.
The axon, on the other hand, extends from the cell body and carries signals away from the cell body while the dendrites carry signals toward the cell body and have numerous synapses to receive the signal from nearby neurons. Upon stimulation, neurons transmit an electrical impulse that passes through the dendrite, to the cell body, axon, axon terminal, and finally, the stimulus is passed (Kringelbach et al., 2020). At the axonal terminal, the axon releases neurotransmitters that depolarize neighboring cells through synapses and by binding to the membrane of the dendrite.
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Specifically, the hippocampus is used to mediate a cognitive/spatial form of memory. It controls learning and declarative memory which covers the memory of facts and events (Malinowski, 2019). The dorsal striatum also helps in memory by mediating the stimulus-response habit memory. Addiction on the other hand is linked to the limbic system through the orbitofrontal cortex and anterior cingulate gyrus (Malinowski, 2019). In line with motor control, the nigra striatal region offers two anatomically and functionally distinct portions knowns as the substantia nigra pars compacta and the substantia nigra pars reticulata.
Other essential components in the central nervous system are the glial cells. They include the astrocytes whose role is to maintain the environment for neuronal signaling by controlling the level of neurotransmitters surrounding the synapses (Hirbec et al., 2020).
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Equally, oligodendrocytes wrap around the axons forming a protective layer called myelin sheath which enhances neuron signaling. The cells also include microglia, ependymal cells, and radial glial whose roles are clearing dead cells or removing harmful toxins, maintaining homeostasis, and regenerating neurons and other glial cells like astrocytes and oligodendrocytes respectively.
Neurons communicate with each other through synaptic transmission. A chemical synapse is registered at the axon terminal of the presynaptic neuron and the dendrite of the postsynaptic neuron (Malinowski, 2019). The dendrite picks up signals and passes the signals down to the axon, into the axon terminals, and into the synapses. The role of the chemical synapse is to transform the electrical signal in the presynaptic cell’s axon into a chemical signal and back into an electrical signal in the postsynaptic cell.
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By Day 7
Complete the 20-question self assessment to gauge your understanding of this module’s content.
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Question 1
Question 2
A, C, and D are misrepresentations of what occurs when you increase Serotonin in the synaptic cleft. There is no effect on the pre-synaptic neuron, and the increases in Serotonin result in a reduction of receptor concentration on the post-synaptic neuron.
Question 3
All of the other options are mis-sequenced in signal conduction.
Question 4
1Neurons are classified in several different ways. From the following statements, select which ones are true.
- The two structural classifications are projection neurons and local inter-neurons.
- Function classifications are made up of two subcategories: excitatory and inhibitory.
- Histological classification includes bipolar, unipolar, and multipolar.
- Classifications using a combination of structural, functional, and neurotransmitter type provide the most robust and useful description.
- Classification by neurotransmitter type alone provides the most useful description.
Statement II would need to include modulatory function to be correct, and Statement V does not include structural and functional classification systems.
Question 5
Answer B is fictitious, D is a type of rapid effector pathway, and A represents G-protein coupled receptors.
Question 6
It is introduced as early as possible in treatment to mitigate the risks associated with nonadherence.
Question 7
B represents antagonism of 5HT1a, C represents a 5HT2a agonist, and D represents what happens when you inhibit SERT.
Question 8
These are signs of an altered mood.
Answer B should read a “discrete” (not multitude) action on the post synaptic neuron.